To begin with,
We can calculate all the values of 2^n where 1 <= n <= 10. We get the values, 2, 4, 8, 16, 32, 64, 128, 256, 512, and 1024, respectively.
We can notice a pattern in the last digit for all the numbers, the pattern follows 2, 4, 8, 6 for every 4 "n" values.
Now, we can predict the last digit of 2^100 based on the noticeable pattern from above. Since the last digits of 2^n follow the repeating cycle of 2, 4, 8, 6 every four terms, we can reduce the exponent modulo 4 to get where 100 falls in the cycle.
Here is how we can do that, 100 mod 4 = 0.
Since the remainder is 0, 2^100 corresponds to the last digit of 2^4, 6. Thus, the last digit of 2^100 is 6.